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Issues | Brain | Oxford Academic
Grin2d mutant mice exhibit a range of phenotypes that mirror the human disease, including cognitive and motor deficits, abnormal brain activity and premature mortality, making the model a valuable tool for studying disease mechanisms.
Brain | Oxford Academic
Brain is currently seeking thought-provoking essays that illuminate aspects of the human condition. Entries can be submitted by clinicians, scientists, students, or members of the public.
MTAP immunohistochemistry as a surrogate marker of CDKN2A loss in brain ...
We included studies on adult patients with brain tumors, in which both the MTAP IHC and CDKN2A gene status were reported from tissue samples. CDKN2A status evaluation was performed by either FISH, copy-number variation plots, or multiplex ligation-dependent probe amplification.
All Issues | Brain | Oxford Academic
All Issues 1878
About the journal | Brain | Oxford Academic
Brain has published landmark papers in clinical neurology and translational neuroscience since 1878. We are committed to increasing our scope: from studies that illuminate mechanisms of disease to novel clinical trials for brain disorders.
Brain's Diseases of the Nervous System | Oxford Academic
The definitive guide to clinical neurology, the twelfth edition of Brain's Diseases of the Nervous System provides detailed coverage of the full range of major neurological conditions, and includes updated sections on genetics, development neurology, and re-written introductory chapters.
Studying human nociceptors: from fundamentals to clinic | Brain ...
Nociceptors are an attractive therapeutic target of painful conditions: their sensitization makes an important contribution to many chronic pain states, they are located outside the blood–brain barrier, and they exhibit relative specificity.
The Effects of Computerized Cognitive Training in Older Adults ...
As cognitive plasticity is thought of as training-induced cognitive change in performance caused by training-induced structural changes in the brain, it is critical to demonstrate structural brain changes along with CT-induced performance improvement in large-sample controlled trials.
Diffuse hemispheric glioma with H3 p.K28M (K27M ... - Oxford Academic
Immunohistochemical stains that were performed at the Mayo Clinic used validated protocols on the Ventana Benchmark Ultra platform (Ventana Medical Systems, Tucson, AZ) with antibodies against histone H3 (mutated K27M) (catalog#31-1175-00-L, clone RM192; 1:1000; RevMAb Biosciences, Burlingame, CA), Tri-Methyl-Histone H3 (K27) (clone C36B11; 1: ...
radiologically isolated syndrome: revised diagnostic criteria | Brain ...
The strategy was to collect all data from subjects with an initial brain MRI that revealed incidental anomalies suggestive of demyelinating disease. Imaging studies were conducted on 1.5 T or 3 T MRI units from different manufacturers.
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