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    * Neurology101 SEARCH *

    *Filter: "Alzheimers"      

      

    Alzheimer's Association | Alzheimer's Disease & Dementia Help
    Alzheimer's Association national site – get information on Alzheimer's disease and dementia symptoms, causes, treatment and care. Join the fight to end ALZ.

    Alzheimer's disease - Symptoms and causes - Mayo Clinic
    Alzheimer's disease is the most common cause of dementia. Alzheimer's disease is the biological process that begins with the appearance of a buildup of proteins in the form of amyloid plaques and neurofibrillary tangles in the brain.

    Alzheimer's disease - Wikipedia
    The course of Alzheimer's is generally described in three stages, with a progressive pattern of cognitive and functional impairment. [33][27] The three stages are described as early or mild, middle or moderate, and late or severe. [33] The disease is known to target the hippocampus, which is associated with memory, and this is likely to be responsible for the first symptoms of memory ...

    What Is Alzheimer’s Disease?
    Find information about Alzheimer’s disease causes, signs and symptoms, diagnosis and treatment, and resources.

    What is Alzheimer's Disease? Symptoms & Causes | alz.org
    Alzheimer's disease is a type of dementia that affects memory, thinking and behavior - learn about causes, symptoms, tests, stages, treatments and more.

    Alzheimer’s Disease: Symptoms & Treatment - Cleveland Clinic
    Alzheimer’s disease risk can pass through generations of a biological family. Learn what causes it and which changes to watch out for.

    What Is Alzheimer's Disease? - National Institute on Aging
    Alzheimer’s disease is the most common form of dementia, a brain disorder that slowly destroys a person’s memory and thinking skills. It is characterized by a loss of cognitive functioning — thinking, remembering, and reasoning — and behavioral abilities to such an extent that it interferes with a person’s daily life and activities.

    Alzheimers.gov
    Find information on Alzheimer’s disease and related dementias. Explore resources from federal government agencies for people with dementia, caregivers, families, and professionals.

    About Alzheimer's | Alzheimer's Disease and Dementia | CDC
    Alzheimer’s disease is the most common type of dementia. Early symptoms typically appear after age 60, and the risk increases with age. Learn more about Alzheimer's disease, including who it affects, warning signs, and what to do if you think you or a loved one might have it.

    Alzheimer's Disease Fact Sheet - National Institute on Aging
    Alzheimer’s is currently ranked as the seventh leading cause of death in the United States and is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning — thinking, remembering, and reasoning — and behavioral abilities to such an extent that it interferes with a person’s daily life and activities. Dementia ranges in severity from the mildest ...

     

     



           * Neurology101 LATEST NEWS *

                        *Filter: "Alzheimers"

     

     
    Head Shape and Alzheimer's; Prenatal Choline and Kids' IQ; Aspirin and Dementia  MedPage Today

    Pathos raises $237M and lands Alzheimer’s drug deal with Tempus, Bristol Myers  Crain's Chicago Business

    What is the Link Between PMOS and Alzheimer’s Disease?  EMJ

    FDA Launches New Neuroscience Program to Improve Alzheimer's Prevention Trials and Support Future Treatments for Brain Disorders  Medical Daily

    Alzheimer’s is changing the imaging business... the complete care pathway comes next  DOTmed

    Study ties estrogen-based menopausal hormone therapy to lower Alzheimer’s risk  Stanford Medicine

    Blood and Gene Test Combo Forecasts Alzheimer’s Symptoms Years Before Onset  Columbia University Irving Medical Center

    Blood-Based Biomarkers for Alzheimer Disease in Primary Care  Neurology® Journals

    Moderate Egg Intake Associated With Lower Incidence of Alzheimer's Disease  Neurology Today

    Different functional connectivity gradients reflect aging and Alzheimer’s disease  Nature

    CSF and Plasma Analytes Reveal Early Clues to Alzheimer’s Development  Cleveland Clinic

    At the intersection of research and clinical care, there is hope for patients with Alzheimer’s disease  Mass General Brigham

    Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration: a case report  Frontiers

    FDA Launches New Accelerator for Alzheimer’s Disease Prevention  EMJ

    National Plan for Alzheimer's and Dementia Gets an Update From HHS  MedPage Today

      

     

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    Common Neurological Symptoms & Warning Signs
    • Persistent or Sudden Severe Headaches — Onset of unusually intense headaches, sudden thunderclap onset, or chronic pain accompanied by nausea and visual disruptions.
    • Numbness, Tingling, or Paresthesia — Loss of sensation, burning, or a "pins and needles" feeling in the extremities, often signaling peripheral neuropathy or nerve compression.
    • Focal Muscle Weakness or Paralysis — Sudden or progressive loss of muscle strength, facial drooping, or difficulty lifting objects, commonly associated with stroke or nerve disorders.
    • Seizures and Convulsions — Sudden, uncontrolled electrical disturbances in the brain leading to involuntary muscle spasms, loss of consciousness, or brief absence spells.
    • Vertigo, Dizziness, and Loss of Balance — Sensations of spinning, unsteady gait, or uncoordinated movement (ataxia), pointing toward vestibular or cerebellar dysfunction.
    • Cognitive Decline and Memory Impairment — Uncharacteristic confusion, difficulty retrieving words, disorientation, or short-term memory loss impacting daily functioning.
    • Visual Disturbances and Diplopia — Unexplained double vision, temporary loss of vision in one eye, or sudden blurred vision stemming from optic nerve issues or brain lesions.
    • Dysarthria and Speech Difficulties — Slurred speech, trouble articulating words, or difficulty comprehending spoken language due to motor speech pathway impairment.

      

    * Useful Government Health Sites:                               
    Key Milestones in the History of Neurology
    • Edwin Smith Papyrus (c. 1600 BCE) — The earliest known medical document describing brain anatomy, cranial sutures, and meninges, detailing head trauma cases in ancient Egypt.
    • Hippocratic Corpus (c. 400 BCE) — Hippocrates challenged mystical beliefs by identifying the brain, rather than the heart, as the seat of human intelligence, sensation, and emotion.
    • Vesalius and De Humani Corporis Fabrica (1543) — Andreas Vesalius provided detailed anatomical drawings of the human nervous system, correcting centuries of Galenic anatomical errors.
    • Discovery of Cerebral Localization (1861) — Paul Broca demonstrated localized speech production functions in the frontal lobe through post-mortem studies of aphasic patients.
    • Establishment of the Neuron Doctrine (1891–1906) — Santiago Ramón y Cajal and Camillo Golgi revealed that the nervous system consists of discrete individual cells rather than a continuous net.
    • Invention of Electroencephalography (1924) — Hans Berger recorded the first human brain waves (EEG), revolutionizing epilepsy diagnosis and sleep cycle monitoring.
    • Development of Neuroimaging Techniques (1970s–1980s) — Godfrey Hounsfield developed Computed Tomography (CT) and Raymond Damadian pioneered MRI, transforming non-invasive brain visualization.
    • Discovery of Neuroplasticity (Late 20th Century) — Researchers demonstrated that the adult brain reorganizes neural pathways in response to learning, environmental changes, and injury recovery.
    Current Neurology Research & Breakthroughs
    • Blood-Based Biomarkers for Early Alzheimer's Detection — Advances in blood tests tracking amyloid and tau levels allow for faster, non-invasive diagnosis before major cognitive decline occurs.
    • Adaptive Deep Brain Stimulation (aDBS) in Parkinson's — Closed-loop DBS systems now record real-time neural activity to dynamically adjust stimulation, significantly improving motor fluctuations.
    • Disease-Modifying Gene Therapies for Neurodegeneration — Novel viral vector therapies target genetic root causes to slow progression in rare conditions like Huntington's disease and ALS.
    • Precision Immunotherapies for Neuromuscular Disorders — Targeted monoclonal antibody treatments offer faster-acting, long-term disease management for autoimmune conditions like Myasthenia Gravis and CIDP.
    • Brain-Computer Interfaces (BCI) for Paralysis Recovery — High-density microelectrode arrays decode neural intent into real-time digital text and prosthetic movement for spinal cord injury patients.
    • Neuroinflammation and Microglial Modulation in Stroke — Investigational therapies focusing on microglial activation show promise in minimizing secondary brain injury following acute ischemic events.
    • Focused Ultrasound (FUS) Blood-Brain Barrier Opening — Non-invasive MRI-guided ultrasound temporarily opens the blood-brain barrier to deliver targeted chemotherapies directly into brain tumors.
    • Single-Cell RNA Sequencing in Epilepsy Therapeutics — Transcriptomic profiling identifies specific neuronal subpopulations causing drug-resistant seizures, opening pathways for targeted drug design.

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